I keep garbage bags in the suitcase. As I put the dirty laundry in, I sort it into different bags. Makes doing the laundry at home much easier...I just dump each load out of its it's bag and into the washer. 
I also pack each outfit in a bag. That way, unpacking is easier - just transfer the bags to drawers. I also don't have to worry about what is in the drawers.
I got one of those big LL Bean toiletry things, which helps me bring a bunch of crap like Pepto, Advil, etc. without having to take it all out.
I try not to bring too much stuff. That helps keep things organized. Can't make a mess without a bunch of junk to mess up!

I also pack each outfit in a bag. That way, unpacking is easier - just transfer the bags to drawers. I also don't have to worry about what is in the drawers.

I got one of those big LL Bean toiletry things, which helps me bring a bunch of crap like Pepto, Advil, etc. without having to take it all out.
I try not to bring too much stuff. That helps keep things organized. Can't make a mess without a bunch of junk to mess up!