I don't leave home without a shoebox sized container that has medicine and first aid kind of supplies in it. It has pain reliever for all the age groups (which is getting easier/lighter as the kids get older), stomach settling meds, a cold something, band-aids/antibacterial ointment, and mostly benadryl. Some of my kids have crazy reactions to bug bites and I like to keep internal and topical kind on hand. In all our trips we've only had to use it once but I like to have it just in case. The price of medicines in vacation areas are ridiculous so I like to be prepared (but I don't carry these into the parks since they have a first aid station in each park).