I have the grand traveler and love the bag. It holds so much and is great because you can fit a couple of pairs of shoes in there, a heavy jacket or even a pillow or throw blanket. However, it is large. It will not fit under the seat of a plane and will count as your overhead compartment piece of luggage, so you couldn't take this bag and a wheeled suitcase as carry-ons. However, if you're looking to replace the wheeled carry-on suitcase, this bag is great! Thanks to the pockets and compartments, I can fit more in this than in a carry-on suitcase.
I also have the get carried away tote and love that bag as well. It works perfectly as a weekend bag if you don't need thick sweaters or multiple pairs of shoes. Basically, you could fit a couple of pairs of jeans, a few shirts, an extra pair of shoes, pj's and a makeup bag. It isn't going to hold anything thick, bulky or big. This bag fits perfectly under the plane seat as long as it isn't overstuffed.
I really recommend Vera Bradley bags for travel. Honestly, I really wasn't a fan of their bags and the patterns and designs and such. But my mom recommended them and I found the grand traveler was the size, shape and in the budget I was looking for, so that's the one I ended up with. I was so pleased with how the bag has held up, how it washes up and how much I can fit, that I have since ordered the get carried away tote and Vera tote. I travel a lot, am rough on my bags, I shove them full and at times they are very heavy, but there is absolutely no strain, tearing, unraveling threads or anything on these bags. They look great and really have held up well and put the more expensive carry-on I've had in the past to shame. I know I sound like a walking billboard, but I really do recommend these bags as carry-ons or weekend bags.