Just an FYI, DC traffic never ends. Even at 10 PM.
Leaving at 5:00 AM from North Jersey on a weekday (if that's whn you are traveling) will put you into the height of rush hour.
DH (and I to a lesser extent) have made this trip probably two dozen times in the past 30 months.
Seriously, the BEST way to make the drive is on a Saturday and Sunday. If you leave around 4:00 AM you'll beat the shore traffic (yes, you'll deal with shore traffic by around 9:00am in central NJ and then along until after your cross the Deleware Memorial Bridge. Your goal is to be over that before 7:00 AM, the earlier the better.
From there you be pretty smooth sailing until you get to just north of Baltimore where you'll hit a little more traffic. At that point I'd
strongly suggest you turn your radio to 1090 AM for traffic updates--if the Fort McHenry is backed up take the Harbor tunnel, you'll end up in teh same place. You want to get onto 295--the Baltimore Wshington Expressway, it will cut some time off, and you'll take it until you cross the Wilson Bridge, at which time You'll be back on I-95.
Keep going on I-95 south until you get to I-295, the Richmond By-pass. Take it.. It looks lnger but it's actually shorter. Shortly after you get back onto I-95 you'll get to Stoney Creek. There's a brand new rest area/truck stop that's very nice--clean, Krispie Kremes, Starbucks, icecream, good place to stop for sure!
From there stay on 95 south. We've found good gas at the El Cheapo Depot in GA, there's a Taco Bell off exit 90. (the inmportant things in life!

) Richmond Hill is also a good place to spend the night. We like the Hampton Inn there.
Sunday traffic is generally very manageable. You'll hit a little bit going through Jacksonville, but on SUnday it's not bad at all unless there's a Jags football game. We stay right on 95 through J'Ville unless we're going to hit it rush hour during the week.
The next traffic you'll hit is in Daytona where you'll get on I-4. Take I-4 west and just follow the signs for WDW, and you'll be there!
There's some construction going on in most states, but in all honesty the worst back-up's we've found have been due to accidents or just volume, and there's not much you can do about that. DH has a CB and a GPS, and that has saved him hours and hours, but for the once in a while traveler it's not going to eb worth the investment.
Let me know if you ahve any other questions.
Anne