This varies
wildly from district to district. It will depend what your state and local rules and policies are.
As far as I know, Michigan (and Ann Arbor) are pretty tolerant of family vacations. However, we decided pretty early on--before our eldest started kindergarten--that we would try to never pull our kids out of school for a discretionary trip. We stuck to that, and it worked out well for us. During the calendar year there are 15 full weeks when the kids were not in class, plus a couple of almost-weeks (Thanksgiving, Fall break). With some advance planning and prioritization, it was not hard for us to take 2-3 weeks of family vacation per year. One was usually a Disney trip, and the other(s) something else.
Most years, our "Disney trip" was to either Orlando or Anaheim during the kids' winter break in mid-to-late February. We also did one Orlando trip during spring break, and a couple of summer weeks. One summer we spent a week in the water parks, Disney Quest*, and visiting the resorts, completely avoiding the heat of the theme parks. Another year was the
DCL Alaskan cruise in August. One year was a week in Paris in an apartment in the 14th arr., followed by a four-night stay at DLRP for the first half of July. We even did Christmas week at WDW one year--not something I want to do all the time, but it was great fun to do once.
There were lots of other trips to lots of other places: Hawaii, Washington DC, the Smoky Mountains, the Outer Banks, Sedona and the Grand Canyon, the Rocky Mountains, etc. etc.
Other people pull their kids and don't think twice about it, and that's fine for them. But, we decided we were going to avoid it, and were able to do so without sacrificing our ability to take plenty of vacations, Disney and otherwise. Some of them might have been a little more crowded and/or a little more expensive than they would have been if we'd been willing to pull them, but we figured that was just part of the cost of having kids.
Once our oldest started grad school, it got much harder for us to all be somewhere together. (She's spending most of her summer
digging in caves in South Africa!) With her brother now also starting grad school this Fall, it will get harder still. But, we still manage. They were both able to join us for a 10-day trip to Boston and Northern Vermont this June. We'll spend a week with each of them separately during their respective spring breaks, and we've invited them to join us for our two weeks in the Hawaiian islands next summer. Turns out the nicer the plans, the more they work to make it happen. ;-)
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*: Yes, I'm dating myself.