It's about a 10-15 minute walk from the HRH to Kirkman and Vineland. Go out the main entrance, make a left, walk down to Vineland and make a right to Kirkman. There is the Walgreens on the corner. There is also a minimart close by (I forget exactly where, you may have to look around a little). There are also several fast food places in the vicinity including McDonalds and Wendys. I walked over there pretty much everyday to pick up odds and ends when they were needed. I walk everyday, so I don't find it far at all.
If you are staying at the Portofino (or want to cut through from the HRH) there is a shortcut. Go past the bocce ball courts and villa pool to the parking lot. There is a small path through the shrubbery that drops you almost at the corner of Kirkman and Vineland. I can't describe where it is but if you walk along the shrubs and keep your eyes peeled you will see it. It is pretty small and easy to miss. I could get to my room in the villa wing to Kirkman and Vineland in about 5 minutes.
Shawn