Ah...a true RIer!
We drove down once, and I will never do it again in the same way. That is, we didn't stay in a hotel either way.
This was over April vacation 2 1/2 years ago. Our oldest was away at college, our middle DD was a Jr in HS and going to Spain with her class, and our DS was in 8th grade and going to the UK with his soccer team. We debated (but not for long) about whether to paint the house that week, or go to WDW...a no brainer!
We ended up driving because we couldn't get good airfare. The days were so specific that we could travel because of when the kids were leaving and returning (normally, we travel in the middle of the week for better fares on SWA). So we decided to drive.
I told DH to get some good CDs to listen to. Found out shortly after departure that he had gotten a 30 hour Physics class on CD!

Actually, I found myself paying attention and it was rather interesting, altho I personally would have chosen something with some MUSIC.
Left northern RI at about 9:30 AM on a Saturday, stopped 3 times along the way to eat and take potty breaks, and arrived at OKW at 7:00 Sunday morning. We took turns, but DH did the majority of the driving. Our room was ready (yay!) so we checked in, showered, and were outside the gates of EPCOT at 8:45 AM. We marveled all day how much energy we had, but we were back in our room at 4:55 PM and in bed and asleep by 5 PM! And we slept through to the next morning. (Originally we thought we'd sleep a few hours and then go back to EPCOT for Illuminations.

)
We left at about noon on Friday to come home, and arrived home at about 10 AM Saturday I think. (Not really sure, but I remember eating at Earl of Sandwich Friday.) I did more driving this time...one stretch of 8 hours. We stopped 3 times on the way back, same as on the way down. (Sometimes I can't get through a soccer game without needing a bathroom; how I managed so few breaks on that trip...

) Then I slept and slept and slept!
Having said all that...I'd never do it again. At least not without more drivers. I worried too much about fatigue. And besides, I wouldn't mind staying in a lovely hotel along the way.