Hi. Not sure how much info I can give as I've only stayed at 1 Deluxe Disney Hotel and that was Animal Kingdom Lodge. I think all Disney accommodation have rooms for people with disabilities, but I think you have to phone disney direct to book these rooms. I have had health issues myself and have always asked for rooms with the least amount of walking. I would also telephone the hotel directly the day before checking-in just to confirm my request. I think most of their hotels have lifts, ramps and automatic doors for wheelchair access etc.
We are a larger family of 6, so we have always had 2 connecting rooms which gave us 2 tv's, bathrooms etc. If your a group of 4 or less, I'm not sure what options you would have, as most rooms sleep 4. So if you wanted 2 rooms it would cost a lot more.
We've eaten at nearly all the Deluxe resorts and find there is a huge selection of food choices at each resort, whether its counter service or table service.
I think one of the Magic Kingdom resorts are great because of the Monorail link to MK and Epcot