We have the plush P&F, and I think DS has played with them like twice. He did sleep with both of them for a while, so we would occasionally hear things like "Yes, yes I am" and "They're the only mammals to lay eggs" over the monitor when he would roll over them, LOL!
We also have the Target motion-activated Doofenschmirtz and Ferb, because I'm a sucker and they make my 14mo laugh. Of course, they sit in the toy box and when anything moves in there, we hear "Curse you Perry the Platypus!"