We found Great Wolf to be close to other attractions if you drive. I wouldn't suggest walking as I don't even know if there are sidewalks.
When we drove to it, it seemed as if you went through an industrial part of town. Once we were at the resort we stayed and purchased all our food there. Our standard room also came with a very small fridge (dorm size) but if we had known we would have taken along some food for meals. It also had a microwave. We did bring snacks of fresh fruit and junk, that we kept in our cooler in our room.
We only stayed one night and when we checked out, we drove around Niagara Falls and found it wasn't that far off by car but you would then have to pay to park elsewhere if you stopped to see anything.
I hope this helps.