I don't see how you could do this. ME is supposed to be a way to get from MCO to the onsite resorts. They don't make any stops at offsite locations, etc.
Your best bet will be to just take your luggage with you to the offsite hotel, and use that hotel's shuttle or rent a car to get to your Disney resort the next day.
You can ask to see if ME will hold your luggage for you overnight and deliver the next day to your resort, or if your Disney resort would do this for you overnight. I know the resorts will keep your luggage during the day, but I've never tried to get them to hold it overnight.
But you will have to find some other way of getting to the Disney resort from the offsite hotel in the morning.