We got a pregnant female once. First separate them now. She will be fertil again once she give birth.
The babies will be born without your help. We were in the room when she had the babies and all we heard was the little squeaks of the new ones. They will look like a ball and be all head. Ours had three babies. The first two born were girls and the runt was a boy. We did have to pull the sack off of the boy. The girls only nursed for a short time. They were eating real food and drinking from the bottle within days of birth. The boy was younger and the mom let him nurse more often and did not wean him as quick. We found the mother liked when we would give her a break from the babies. She let us hold them from the day they were born.
We found it was best to hold all three at once as it seems to comfort them. Within a few weeks we had to remove the boy to prevent him from mating with his mother or his sisters. They can get pregnant at a very young age.
Other than putting the mom and babies in their own cage, there really was nothing we needed to do. I did take the mom and the few week old babies to the vet, to make sure all was well and to verify that I had sexed them correctly. I had.
We set out finding them homes as soon as they were born. We were lucky we found homes for all. The pet store would have taken them, but DH would not do that. He was so worried they would be put into bad homes.
Our piggies had babies twice, and our experience was very similar.
Both times our babies were born during the nighttime, and we were completely unaware of the birth. We really didn't do anything special for them.
We didn't have a separate cage for the mom/babies: Our guinea pigs lived in a very large wire mesh cage, so we bought another piece of wire mesh and "sewed" it in with wire all the way around, essentially making a small "room" for the daddy on one side of the cage. The daddy pig LOVED those babies. He taught them to wiggle and jump (they looked like popcorn). They'd lay up against one another, their sides touching through the wire.
In fact, the daddy pig seemed so loving that when the pair had a second litter on the way, we decided it was
not necessary to put the wire divider back into the cage -- after all,
we had the daddy pig who liked his babies! Yep, he
liked them all right. He liked them so much that he ATE the second litter before we ever saw them, leaving enough evidence behind for us to know that we hadn't imagined the pregnancy (well, we assume it was him because the mama pig didn't do it the first time). So, just in case you're wondering whether it's really necessary to separate daddy pig, the answer is YES!
After that pair died, we got another pig -- just one this time -- and after we'd had her a week or so, it became apparant that she was ALREADY PREGNANT when we bought her! We didn't realize what we were in for when we picked that piggy! The point, of course, is that you MIGHT have two females.
It's been so long ago that I don't remember what we did with the babies, but they were lots of fun!