I've always been one for stuffing as many pics on a page that I can, which is why I rarely do pic matting/borders. I've recently started doing digital scrapping which is awesome, since you can resize your pics on the fly and have small images that help tell your story of the page, without "stuffing" them all in.
Try cropping your pics as much as possible, so that a bunch of them are smaller, this will bring out the person or thing you want to showcase, and eliminate wasted space. Get a cheap straight cutter to do this easily.
Don't be afraid to have a huge book. Make sure you use a post bound book, so that you can make it really fat by adding extra posts, which is very easy to do, just screw them on. I have several trips scrapped in one book and it's a couple inches thick. I like to keep them together, so I can just be happy looking through that book.
You don't have to scrap all your pics. Pick out the ones that are special and help tell your story. I pick themes for each page/2page LO based on what pictures I've taken. On my last trip I had a lot of WL pics, so I showcased WL, and I had a lot of fireworks pics to make a firework page, etc. I also try to highlight different things then on previous trips.
Don't be afraid to add things together from different times during the trip. Instead of scrapping a lot of pictures from a single character meal, maybe make just a 2 page LO on all your character meals. You may leave out a lot of pics this way, but you will still tell your story in a smaller amount of space. Just don't leave out one child... they'll notice!!!
One of my early pages that is one of my favorites is "A Parade of Parades" where I had pics of all the parades we saw during that trip in 2000, including Tapestry of Dreams and the MK parade. That was back in film days, so we do have many more photos now of each parade and I will probably spread them out to their own LOs, but if you were looking to condense space, that is one way to go.
Hope this gives you some ideas. Would love to see what you come up with when you finish!