A lot of how ill one becomes with covid also depends on which variant is responsible. DD had covid in the "first round," in January 2020. She was terribly ill for about 2 weeks: Fever >101F, loss of voice, terrible congestion, complete loss of taste and smell, blinding headaches, debilitating body aches, fatigue, migraine. She had repetitive, crippling migraines for over a year and still hasn't fully recovered her senses of taste and smell. I have had covid twice; first in Dec 2021 and most recently tested positive on May 22nd. I am pretty sure the case in Dec was the first omicron variant, based on the initial symptom being scratchy throat and headache. I was sick for about a week, ran a fever of 99F-100F, was very congested and achy, was out of work for 2 weeks. Long term I had exhaustion for several weeks and brain fog for several months. The second time I had covid was weird. DH was sick, tested positive, took an antiviral and was on his feet in a matter of days. At the same time, I was sick as a dog, worst cold I've ever had, sore throat, sinus issues, headache, totally congested- and tested negative by at-home testing every other day for 2 weeks. As I was testing negative, I continued to work. On May 22 I went to walk-in care for a knee issue, and as I was slightly congested they swabbed me and ran a PCR, and I was positive. No symptoms at that point, but positive. The doctor told me that they are finding that a variant of the omicron variant isn't showing up as much on the home tests- meaning there's probably a mutation in the antibody binding site, so the home tests don't "see" the nucleic acid and therefore give a negative result. PCR is significantly more sensitive and detects genetic material from the virus whether you've been recently exposed, are ill, or were ill and still have minimal amounts of RNA running around in your system. She said she thought I probably had covid when DH did but it was the omicron variant (the variant's variant) and didn't show up on the home test. Makes sense.