We just drove from the area to Tampa on a Saturday morning. Heavy traffic, but not slow, except for the durn rubberneckers watching a roadside cleanup---and that only added maybe 15 minutes or so.
"Gawrsh! An accident! Let's slow down to look!"
Give yourself some extra time to get back, but you should be fine. I wouldn't do a TPA roundtrip to save $100, but I would to save $200. Go for it.