The location of the Nick Hotel is great. Access to the parks via car is very easy and quick. Probably faster than the disney buses, except for MK which drops you off at the monorail while the dis buses drop you off at the door.
But, it is the only good thing about the hotel. Very Pricey, noisy, lousy food.... you could do much better elsewhere unless you are really set on the Nick theme for your kids.
The Hotel has gone down hill since switching over to Nick Hotel.