We have

just about yearly for the last 5-6 summers with Captain Scott.
It's a 3 hour trip at low tide. Along the way you'll see dolphins as well as native birds which Scott will point out to you. This is how we've chose the beach combing trip over the dolphin tour, because for the extra money, you get the best of both worlds, in our opinion.
When you get out the Dufuskie Island, Scott will pull his boat as far up to the beach as possible, but you still have to get off of it and into knee deep water. It's a short walk to the beach, where you never know what your going to find. We did it in March this year, and saw an Eagle soaring overhead. We bring along a bucket to put our shell collection into to get back to the resort. We've done this so many times that I always say we're not picking anything more up, but we always do, as it's hard to resist a beautiful starfish or sanddollar laying right on the beach.
Anything you pick up with the intent to keep has to already be dead.
Along with shells, we've seen our share of "live" creatures. Sand Dollars, Various types of Star Fish, Sting Rays, Fiddler Crabs, Blue Crabs. Scott has always walked along with us pointing out things that we would have walked right past has he not stopped to point out to us.
Here are some pictures of our trips: