I bought a new Maytag washer and dryer set in May. The washing machine is HE, but DGF makes our laundry soap so we don't have to spend an arm and leg on detergent.
The only major difference with the HE detergent is that it does less sudsing than the normal stuff.
One of DGFs sisters friends works at Whirlpool (who also makes Maytag) and says that most of their models have a de-sudsing cycle that makes it so you don't have to use HE detergent, it just takes longer to do a load of clothes.