i assume you mean a carry on bag check...
the OP was asking about luggage checks...
the fact that you have to go through security again happens in many airports when you change planes.....this is also true in schiphol airport (amsterdam), but the OP wanted to know if they'll have to collect luggage, which they won't have to do until detroit.
by the way, as sucky as degaulle is,
detroit is the opposite....a very easy airport to navigate...
if memory serves, when you come out of customs in detroit, you'll be at the high end of the terminal (the higher gate numbers)..
depending where your departing gate is, you can either take the moving sidewalks, or the overhead peoplemover....
there is an internal train vehicle.....it's a bit hard to notice....
but it's inside the terminal....over your head....you take an escalator to get up to it...
it has 3 stops: either end of the terminal and in the middle...
but i rarely use the overhead train....i usually just walk and hop onto the various moving sidewalks...
the terminal is one long long long terminal.....well...not entirely true...
there are two or three smaller parallel terminals that you go underground to get to ...
but that's only if you end up going out of one of them...you get to them from the middle of the main terminal..
but i'm making detroit sound much harder than it is....it's a very simple, clean, open, nice airport - surprising considering how truly awful the city of detroit is (if someone has a spare nuke, they should aim it there, and let the city start from scratch

- the saddest city in the world....and what a waste of a beautiful waterfront...anyway....former detroiter and my rants)..
but the airport is very nice....and very easy....and detroiters are very nice and very easy and very helpful....just ask anyone in the airport and you'll get an answer!!! (although detroit accents are horrifying!!!! ask Wayne, he's heard me talk....really a horrible horrible accent!!!)