Weather aside, traffic on Christmas Day is a huge risk!
The year we lived in Jacksonville, FL, my mom came down for Christmas, but had to drive home on Christmas Day. Her normally 6.5 hour trip back to SC took 13 hours! NOT a fun way to spend Christmas day.... It wasn't weather, nor an unusual amount of accidents....just shear volume!
Coming from such a long way, I don't think I'd do it. It could end up taking you 2 days to get there. Not a fun way to start (or end!) your vacation or Christmas....