Ok! We just did this with the vacuum Space Bags. We have small suitcases on wheels.
We loaded the 1st layer of clothes, jeans, then fitted the bag into our suitcases, and add shirts with underwear placed in the folds in case the space bag was removed from the suitcase.
Once we had our clothes in and were ready to use the vacuum, we placed the cases on the floor
[This is the most important Step!!]
Then as you vacuum out the air, you stand on the bag and clothes to work out any lumps, and get everything compacted, then seal it. We used new space bags so they didn't leak. We knew we were only taking one suitcase each, so we could board the plane with them. No accidents happened.
When we got to the Hotel in San Diego, we opened the space bags and used clothes for 3 days, but everything was so compacted it stay that way. But when we had to leave, the hotel didn't have a hose vacuum. No big deal!! They were in the suitcase so we sat on the bags and worked the air out so we could zip the suitcases.
But we also had plastic laundry bags from the hotel to use for laundry and a car to get to DL.
At DL we did laundry so we started with fresh clean clothes. So at the end of our trip we packed the used clothes in the space bags. Then used maintenance depts Shop Vac, to seal the bags while walking on the lumps and compacting everything. Then I packed my clean clothes around the space bag.
I think I liked the Giant Zip-lock bags better for packing, they fit better in the suitcase. We use the sit and squish method, then finish zipping.
I also like the Travel Space Bags, but rolling only works till most of the air is out, then you must use the sit and squish method.
We all had 1 extra bag, Dh had a tummy pack, Dd and I had large bags that held our purses, music, Disney Docs and my planning Folder with all the flight info, hotels, google driving maps, passes, coupons and a sweat shirt.
Plus I had 1 more medium size bag with All my Diabetic supplys in it including Special K bars, and Star Crunchs both saved me 3 times from diabetic lows.
As we never Checked our bags they were only x-rayed at our local airport and at LAX. Then we boarded with them.
No one thumbed through our clothes or broke the zippers, and stole what they liked.[local tsa agents arrested and fired for stealing, cameras and medicines and the like from suitcases that were checked!!! BIG new story here!]