Having just stayed at the Grand Destino Tower (Standard View Nov 16-21), I must say it felt "very deluxe" even though its moderate class. The typical rooms are supposed to be slightly smaller at GDT (314 sq ft at GDT vs 348 sq ft at GF), but really didn't feel it due to the hall walking into the room (gave us another option for where to put our empty luggage, besides under the beds). We had plenty of space. It didn't feel much smaller than rooms when we stayed at the Polynesian and Yacht Club. Just no day bed/fold out at GDT.
We had a friend join my wife and our son, so the batroom setup at GDT wasn't ideal. Only the toilet was separated... So when our friend was in the shower, my son and I couldn't brush our teeth or use the sink area. In other resorts the toilet and shower were in a room, so we wouldn't have had that issue.
I can't speak to busses at GDT as we used our car all week. I was surprised with how centrally located it was for EP, DHS and AK. No more than 6 minutes drive to either of those parks. MK was about 8 or 9 minutes. We didn't time the drive to Disney Springs. I can't see the buses taking much longer (our friend was a slow driver and Disney busses were passing us). At GF, other than MK you use busses for everything, and being next to MK, you'll have a longer ride to EP, DHS and AK. While CSR is a larger resort (more than double the total rooms of GF), it depends on how much of it is opened. So that will impact how long or short the bus lines/waits will be. We didn't see anyone at the tower's bus stop when we left in the morning.