My daughter just flew with our granddaughter who was on liquid meds which had to stay cold. She took it in an insulated carrier with a couple of frozen gel packs. It was not a problem. Plus since we were also traveling with an infant (3 months) had forumla too, still no problem. Plus our son takes liquid meds (10 individual days worth), still no problem (he did carry his in a plastic bag). Everyone had medical letters in case it was a problem. It wasn't. We left from Dulles/Wash. DC. Only had the formula coming out of MCO as the meds were done. No problem again. So our family pretty much covered most scenarios in one trip.