Just a note your donation (although generous) is not tax deductable.
In regards to options, I have spoken with Make-A-Wish before and although they would love to accept the donation of points, they directly would be unlikely to use them because most of those who go are placed in housing in Disney that is supportive to life-care needs of those going. If they were going to use them it would more likely for a fundraiser to raise general capital at a silent auction or similar, and they would request obviously some guidelines on acceptable timeperiods, room size, location, etc (it would be a lot of work on the part of the donor).
One other thing is that if you were going to give the points as a transfer, most likely they still would be unable to use them because of the one transfer (in or out) per year, so even if they already had an account they used, it would be hard for them to use a small amount of points granted to them without the ability to obtain more points via another transfer.