We have flown 3 times and are driving for the 6th time this Summer from NH (takes me a little over 30 hours).
Advantages to driving:
Lots of family time together.
We play games along with a lot of other things.
Cost- We save about $1200 (flight,car rental,food,ect)
Food- We bring a large percentage of our food which we
cook in our condo. Saves a lot of time and money.
Car- We can load our minivan to the max with everything
we will use.
Time- No schedule, we leave when we want, return when
we want.
Airport- None of the airport hassles.
Advantages to flying:
Only one, you get there quicker
Advantages to driving:
Lots of family time together.
We play games along with a lot of other things.
Cost- We save about $1200 (flight,car rental,food,ect)
Food- We bring a large percentage of our food which we
cook in our condo. Saves a lot of time and money.
Car- We can load our minivan to the max with everything
we will use.
Time- No schedule, we leave when we want, return when
we want.
Airport- None of the airport hassles.
Advantages to flying:
Only one, you get there quicker

I'm the only tiny one in my family of four (about 5'), therefore I was able to nap with no problem.