Your main problem will be the aforementioned construction through Macintosh County (and to some extent Glynn County) in Georgia. They are both south of Savannah, and in any event, it's a pretty tight road through there though (jersey barriers on both sides with no where to go, plus bridge construction).
(I live in Camden County which is below Macintosh and Glynn--watch out of the County Boys, they are thick on 95 in Camden County)
It's about 30 miles or so, if that, then you're clear all the way to I4---
Depending on what time you get to Orlando--well, it has the potential to be ugly...