The "southern" route adds 100 miles and 2 hrs of driving but here is what it plotted.
I-70 east to Salina, KS
I-135 and I-35 to Dallas
Pick up I-20 east to Jackson, MS
Non-interstate over to Mobile where you pick up I-10
I-10 to I-75 then south to the turnpike and into Orlando.
1953 miles/29 hrs without stops.
I'm too cheap for that and I spend enough time towing to races all over the midwest and east. If your Class A gets 5 mpg, that's over $2800 in gas in todays prices. I'm cheap and enjoy my time AT the destination, not getting there. I enjoy flying, but it's had to get 2 racecars on a plane and for us, it's cheaper to tow the 5th wheel to WDW than flying and staying in a resort.
Sounds like you're somone that enjoys the travels. Go for it and enjoy. If you come through St. Louis, do pick me up!
j