DS10 has ADHD and is on meds, don't know how your nephew controls his, so I don't know what does or doesn't work with him. We let DS take a small hand held game, not the game boy didn't want to chance losing it, to play while waiting for our seating at the TS dinners. Most of the time, he didn't play with it, had to much fun looking around. We did TS at O'hanas, PSB breakfast, CRT dinner, Captin Jacks, Sci-Fi (he loved this one), Boatwrights, and Donalds Breakfastosaurus (loved his one as well).
We also let him earn spending money while at disney. He knew that if he ate his meal, let us eat ours and didn't get out of his chair, except for character meals, he would earn 5 bucks. So, by the end of the week, he was able to earn an additional $65.00 dollars.