So, your dear friend has an *** for a husband and his neice and they make everyone else miserable. However because of the love everyone else has for each other, you all put up with it as best you can.
That stinks.
Ok, let's see, ooooh, next time she asks for sleeping pills, I might just be persuaded to give her some. Although I don't know of any safe ones that will knock her out for a week. Hmmmm