We just did our 6th trip (Greece, Ireland, Winter in Wyo, Grand Canyon, Knights & Lights, SE Asia) and some of our favorite moments have been covered but I will put in a plug for SE Asia since it seems like a trip that does not get much discussion on the boards--it's wonderful--go!
Making offering to the monks in Laos was a moving and wonderful experience. Laos is someplace I would have never visited without
ABD but it was a truly fascinating and beautiful country. In Vietnam, seeing the Cu Chi tunnels and realizing the struggles of the people there and then having a beautiful lunch outdoors in a remote part of South Vietnam was unforgettable. The history and beauty of Hanoi was also amazing and I was surprised how I was affected by seeing Ho Chi Minh's tomb. Siem Reap is a wild ride and a great way to enjoy the last stop.
I could not agree more with the poster that said the Itineraries do not do the activities justice! Some of the things that I thought would be meh were just amazing. This trip has probably been our favorite.