Didn't really bother us much. We aren't remotely religious, so we're in the group of "just another sunday". We decided to go get the second season of Game of Thrones and be lazy all day, and drove to Target because it's the closest store. Saw they were closed, shrugged and said "oh yeah, Easter" and went back home. I plan to go back there today to make my purchase.
I'm not going to boycott Target because they chose to observe a religious holiday that I don't. (other than in the commercialized sense...I like dying eggs and eating candy!) They were one of the very few places around us that were closed yesterday. We took our dog to get groomed at PetSmart and the salon was busy as heck.
I think it is up to each individual company what days they choose to be open or closed, just like it's up to them what their hours are. Regardless of their reasoning, be it religious or something else, it doesn't really hurt me at all. It doesn't change my opinion of the company. I shop based on price and convenience, not how that company chooses to observe a holiday. I think i'd only have an issue with that if it were a discrimination issue where, for example, Christian got paid leave for all the big holidays, but Jewish people had to take unpaid days. Unless it's something like that, then what does it really matter? Either be happy that a company is observing something important to you, or be accepting that companies have the right to choose to be closed and go shop somewhere else that day.