I come from the west coast and tend to take short trips; not enough time to really love Eastern time. I've made EMH or rope drop when arriving on a red-eye, which is a nice way to start off the trip.
But if it's a sleepless flight, that can backfire. My friend and I landed around 5:30am, got to the MK by around 7:30am, and then proceeded to slog through the day. By the time we got the text notification that the room was ready, we were sitting at the Laugh Floor, heavy heads miserably nodding in a zombie state, foggily disconnected from the show.