I'm a run/walker. Nothing impressive, about 20 miles a week. I have a knee issue, so I have taken 1tsp. Glutamine after every run or workout for the last few years, and it does wonders for muscle soreness.
I also added a B-complex to my daily vitamins, and I cannot believe how much better I feel daily. I am a skeptic when it comes to supplements, but a separate B-complex really does work. More energy, better mood, just all around feel better. I can tell early in the day when I forgot my B vitamin. My wife feels the same way.
Other than those two specific items, I take a multi, and a separate E vitamin.