I'm going to throw in my 2 cents and that's about all its worth.
There are a few unknowns here. Are you flying into/out of Orlando? If you are you can take the DCL bus to the port directly and you can take the bus back to the airport directly. You can also take the DCL bus to a resort after the cruise. As of now, there will not be a Magical Express in 2022 so that is a can of worms for many. Something to think about.
Now, we took our adult children and their spouses a few years back and decided that we would stay at WDW for one night after the cruise. This was partially because you need to be off the ship by 9AM and the bus ride to the airport is about an hour. Our flight would not leave till 5 PM. That would leave us sit there for quite awhile and while I like the airport, I don't like it that much. So we went to WDW, spent the day at the Magic Kingdom, stayed one night, relaxed the next morning, had a swim and caught ME to the airport after lunch. It was a nice taste of WDW without being over whelming and filled in the down time.
Now, as I stated earlier, there is no longer going to be ME so that is out. I do believe, and it's arguable, that there will be some form of transportation on offer as a pay option.
You just need to figure out what works best for you. If your flight is later do you want to hang out at the airport? There is an option of renting a room at the Hyatt, that would give you a place to have a nap, shower, swim and you would still be at the airport. Would you prefer to spend that time doing something a little more fun? Then plan at least one night and you can make at least one park.
Whatever you decide I'm sure you and the family will have a blast! We are taking our family again in March 2022, always assuming Covid is under control and our country lets us out. It's a 7 nighter with a planned 5 night stay at WDW before the cruise. Depending on flight times home, we may just get a day room at the Hyatt, I'm sure we will all be tired out by then.