Yes, we just did this a few weeks ago and they were TOTALLY accomodating. We were two adult couples with no kids, and so it wasn't even super important that we be right next to each other - we just asked to be "near" - as in the same building or something - we just didn't want to be spread far across the property from each other. They managed to find us adjacent rooms anyway, which was very nice.
I found the staff to be very helpful and willing to get us what we wanted in general. That said, I went in with a big smile and a polite request, not a "demand" and I expressed my gratitude for getting us just what we wanted. But I'm of the mindset that you get more bees with honey than with vinegar
I'm sure most people are nice too but we saw enough "nasty customers" while on this vacation that DH and I had to shake our heads.
This is off topic but while picking up our rental car, there was a woman next to us at the counter getting her car and the agent she was working with was very polite and said "Ok, Mrs. so and so - here is your paperwork" and before he could finish his sentence, she cut him off angrily, "It's MS! I am a MS, not a MRS! I take it PERSONALLY that you call me a MRS! And continued to shout and make a scene because the poor agent made the mistake of calling her Mrs.

. That was just one of many "crazy" people we saw on our trip this year....
Thanks Bellamouse for the information. I don't care about a view as much as being close to each other. My first request was proximity, then at least one room with a fireworks view.
About the off topic...As for people being "crazy", I never ever start out as the bad cop. I don't care how bad my day is, I try not to get angry. Unless I'm accused of something...
On a trip to Atlantic city for the weekend with my wife, we discovered that a previous occupant had urinated in the bed. The mattress was not wet to touch, but after laying in it for 5 minutes it was obvious. Long story short, the first hotel personnel to arrive were from housekeeping, and they started searching our room. I asked what they were doing, and they insisted we had a child with us in the room. I politely informed them that we didn't have children (it was before our kids were born). They kept searching. The managers told us they would move us to a different room. It took an hour, and they told us they they confirmed that we did not have children with us. I asked what they meant by that, and was told that they reviewed security footage from when we checked in, and each time we returned to the room. That upset me a bit, and I said to the manager something along the lines of...my word means nothing when I tell you I don't have children to the point you involved your security team to verify, but you fully believe I wouldn't urinate in the bed for fun? He ended eye contact, and a different manager ushered us to our new room We were upgraded to a suite (which was a totally different adventure), given a $100 refund on the room, and a gift card for dinner at one of the hotel restaurants.
I also typically try to be on my best behavior and mind my manners, but sometimes... sometimes you have to take a stand. When my wife was 8 months pregnant with our first child we visited the Baltimore aquarium on a Saturday. It was a busy day, but nothing too bad. Most of the patrons were smoothly flowing from one exhibit to another almost as if we were in a queue. Most of the adults would stand away from the exhibit to let children up to the glass for a view of the occupants. I say most because there was one family who didn't feel they needed to wait, or rather one wife/mother. The first time I noticed her was when she speed walked past me and forced herself upon another couple who was looking at a tiny exhibit. No "excuse me", no apology, but this overwhelming feeling the she deserved to be there. The couple slid out of her way and she called her daughter (around 10 years old) over to see as well. The couple moved to the next exhibit, but as we were in a free form queue, they were always nearby. I witnessed the woman do this a few more times to different people, including children. I was unaware at the time, but I was the next target. I am 6'2" and around 230, and I have very good balance, so for an average sized woman to knock me into my pregnant wife, there has to be some force behind it. I turned around and stared at her angrily. She didn't notice, but her daughter did. Over the next few exhibits I heard her daughter requesting to wait their turn to see the exhibit, but the requests fell on deaf ears. The final straw for me was when she pushed through an elderly woman with a walker. The next exhibit was large, there was plenty of room, and you could be right against the glass. Again this woman pushed her way to the glass going through that first couple again. They moved over a bit against the glass so there was a little bit of room between them. I looked at my wife and said...I'm going to do something, and it might embarrass you, so I understand if you want to stand away from me. She moved to the rear of the room asking me not to do anything because karma would catch up with her. I told my wife that maybe I was karma. I turned, and as if the sea of people had parted just for me, I had a straight line to her. I swiftly crossed the area, loudly proclaimed that I had never seen a (insert one of the species in the exhibit) and threw myself against the glass as if I was an over-eager child/hockey player. The collateral damage I could feel as the left side of the rude woman was pressed and held against the glass for a good couple of seconds. I heard her tell me that was rude as she walked away. I turned and looked at her daughter, gave a wink and a smirk, and she smiled back as if she was glad it happened. The woman's husband stared at me and nodded his head a few times. From my left I heard the guy in the first couple say "good job". Most of the people in the area were smiling or giggling as they had all seen her wrath. We didn't see her again until the dolphin show when they walked towards us on the stairs. I watched her as they got closer and she saw me. I grinned, and she looked away.
As I said, I usually don't get angry. However, if someone else decides to get "crazy", sometimes a subtle or not so subtle reminder is all anyone needs.