We did one once, split between AKL and Poly due to Poly not having all the nights we were staying. Took the first 3 nights at AKL and then switched to the Poly for the next 8, I believe nights. Did not like the process, this was a few years ago and we checked out early to get to the Poly which we prefer, did not care for AKL and was not informed until checking into the Poly that our luggage and stuff would not be delivered until after 3 pm, this might have changed since then, but was a big inconvenience to us. We're of the kind that stays 8-12 nights and like to unload all our things, stash the food and drinks and set up the room with all our necessities and then just explore WDW.
We consider WDW our home away from home so its the necessities we bring and layout that aren't fun to pack up plus clothes and move to another resort to do again. I'm glad we had the experience once and won't do it again. If we're interested in another resort, we'll plan another vacation and stay there another time. Its a personal thing splitting stays but its not for us.