Val & I did this
ABD as part of the special DIS Boards/
Dreams Unlimited trip which combined the SF weekend with Back Stage Magic. This is the tour that Kevin mentioned earlier in this thread.
In short, SF was very fun and exhausting. You get a really great experience of the city and the surrounding area. Our guides were Hanneke and Summer Rose, both of whom were spectacular. They worked well together (along with a special SF local guide Eleni) to ensure that the group got to see the highlights.
Parts of this trip were customized for just our group so I won't go into all the experiences since they might not be the same on a "standard" trip. We thought the visit to the Disney Family Museum was a really special part of the trip. Wish we had more time to wander through all the exhibits there. There were several meals included in the trip at some SF restaurants which were fun dining experiences. Our hotel was the Fairmont, which is like a grand old dame of SF. We upgraded our room on arrival to a tower room ($50/night extra) and had beautiful views of the bay.