We are in Central Indiana and looking for something to do over Fall Break. Basically, we get a long weekend (Thu-Sun). We aren't doing Disney this year since 1-we went in 2010 & 2011, 2-there aren't any discounts, 3-airfare is ridiculous, and 4-DD (HS sophomore) has some tough classes 1st trimester this year so we didn't want to take her out for extra days (which we do for Disney). We are thinking of doing a long weekend in Chicago.
Have fun planning your October trip....wherever you end up going!
Cleveland? Rock and Roll Hall of fame, http://meltbarandgrilled.com/, http://www.goodtimeiii.com/cms/
The University Circle area is full of great museums too I hear, but we didn't venture out of downtown. Cedar Point if it's open fall weekends and you are into roller coasters.