Since it's just a weekend trip, I would recommend a hotel suite over a timeshare or townhouse rental. Many of those properties are "self-catering," meaning you get a starter set of supplies such as toilet paper, soap, etc. If you run out, you would need to replace them yourselves, meaning a run to a store or bringing them in your suitcase. Also, quite a few of the places charge a cleaning fee if you stay less than seven nights. For a quick weekend trip, I think you would be most comfortable in a hotel suite with daily housekeeping and a free breakfast. Try looking at places such as Quality Inn and Suites, Staybridge Suites, Springhill Suites, Hawthorne Suites, and Homewood Suites. Some have multiple locations around the Orlando area. Also try doing a search on hotels.com or Orbitz.com so you can quickly compare hotels and their rates. Many hotels that come up on the search will include options for suites with multiple beds and two bathrooms.