If my choice were between a
connecting flight to John Wayne Orange County Airport (SNA) or a
nonstop flight to Los Angeles International Airport (LAX), and the price were about the same, I would pick LAX.
SNA is closer to
Disneyland. It's a pleasant, medium-sized airport. You can rent a car without having to take a bus. The problem is that nonstop service to SNA is limited.
LAX is a mega-airport, with all the crowds and inconvenience that you might imagine. LAX has nonstops from far more airports than LAX.
As soon as you have to change planes, your travel time increases, usually by a couple of hours each way, and you introduce the very real risk of missing your connection and having to wait at the connecting airport for a later flight.
Sometimes (but not always) connections are substantially cheaper than nonstops. In that case, I would prefer a connection to SNA over a connection to LAX.