Hi, just wanted you to know. My 3 year old is on a lot of medication too. She has to have a nebulizer everyday. I do not know if they require a note or not, but the doctor thought that it was best. I had a separate carry on bag with all of her medecine and her nebulizer. Never know when you are going to need it and you don't want to take the chance of it getting lost with all of the other luggage. I hope that you have a nice trip. I also start planning months and months in advance.