We did Philly to Disney this past summer, and stayed in Savannah at a Marriott off of 95 (search Marriott 95 South). At this exit, there are several hotels and a few restaurants, including a Cracker Barrell (which are everywhere along 95). We arrived around 8 pm (left our house at 7 am, stopped in Virginia for lunch for an hour and had a few bathroom breaks along the way.) The Marriott was nice and clean, had ample room for the 5 of us and had a mini-fridge for me to store our cooler contents and refreeze our ice packs. We only paid about $90 for the night.
On our way home, we stopped in Hilton Head.
This year, we are flying.

Flights on Frontier out of Trenton are probably just as cheap as gas for the trip.
FWIW, though, our neighbors drive every year and do it without stopping with three young kids. They say they make it in about 15 hours from door to door, but we think 16-17 hours is more what it would take us to do it in one shot with a break for a meal and a few other stops.
Never again for me, but good luck!