I grew up in California and we only had Hostess, but my husband grew up in New Jersey, and had Drake's. I was thinking it must be regionally, but from the answers from all over the country I'm thinking it's not.
Drakes is a Northeast brand and Hostess is Country wide. They are all the same. Hostess,Drakes and Wonder Bread are all the same company,IBC. A ring ding,ding dong,yodel and hoho are all made in the same place on the same line.Only very slight differences in the ingredients,that being Hostess products use animal fat and Drakes doesn't.