I collect the Snow Village pieces. I think at last count we had over 100 pieces, including accessories. I only put them up at Christmas, and it takes at least 2 full days to set it up.
I have tons of counter space in my kitchen, and I set up all the "downtown" pieces in there, like the bank, post office, toy store, fire station, church etc.
In my dining room I set up the "suburban" area with all the uniques homes, ice rink, basketball game, tree house, etc.
But my favorites is the "wilderness" collection which I set up in my living room. My husband built a display area specifically for it. I have the hunting lodge, ski lodge, fishing cabins, about 8 pieces of the winding river with bridges and animals, the tree farm, log cabin, skate shack etc.
I also have tons of trees and lots of little accessories like garbage cans, light posts, cobblestone walkways, etc.
It is a ton of work, but we got smart a few years ago and made a map of how everything was set up. It helps not to have to try and figure out how everything fits every year.
Oh, I also have the Halloween Village, but not nearly as many pieces, probably only 20 total with the accessories.