That depends. If you get motion sickness, I would stay away from the Teacups & Astro Orbitor. If you are afraid of heights, Tower of Terror may bother you. It is an awesome ride, though. If you don't like to go upside down, RnR coaster may not be for you.
Mission Space is in a class by itself. I've read where some people who suffer from motion sickness weren't bothered at all by it. I, however, was extremely nauseated, lost all color in my face, was shaking all over and had to sit on the bench near the exit for about 20 minutes before I could even move.