I assume that to do that, your wife needs to be listed on the second room, so the room key with her name on it will be attached to that room and those dates. Without having to worry about tickets or dining plan being attached makes it easier, but if you were to have room charging privileges it could get sticky. If your wife is shopping after they've left and wants to charge to her room, she's either got a room key for a room that she supposedly checked out of already, or one with someone else's name on it. If you are to attend an EMH after your friends have left, that might be an issue, too, though it doesn't seem they've been checking room keys too carefully for that.
So I think the official answer is no, but I guess it can be done.
Good luck! Do your friends have
AAA? Some of the AAA and general public discounts have come pretty close to AP rates lately.