I have severe motion sickness and dramamine is the only thing that works for me. I have taken it all of my life. It does make me sleepy, so I just sleep. It has to be taken every 4 to 6 hours, so for me it wears off in that time which is fine (I just retake for longer trips.) I think a lot depends on the severity of a persons illness. I agree, try the bands for a shorter trip, but have dramamine just in case. People who don't get motion sick have no idea how awful it is.