When Vioxx was taken off the market, I tried to go without (don't like meds if don't have to). After a few weeks, I could barely get out of the car (osteo in knees). Alleve (or generic) was suggested as good alternative. I started, one in AM, one in PM. After about a week, I was fine again.
Interesting sidenote to the Cox-2 inhibitor meds (Vioxx, Celebrex and Bextra)...they were primarily made to provide pain management, roughly equal to the OTC alternative pain meds (Alleve, Anacin, Tylenol, etc), but without the potential GI upsets. The marketing folks however, pushed them as superior pain meds, in pain reduction ability, to the consumer, not really promoting to much extent the true reason for thier existence, low/no GI upset. Consumers asked for, and received, the greatly more expensive Rx's, thinking they were getting better pain reduction. The greater population does not have GI troubles with OTC. Another marketing bonanza created through advertising.