Adderall is the same thing as Dexodrine (generic), which my DH is on. He went to adderall for a while, and while longer lasting, it also was much more expensive for us. Like someone mentioned, these drugs are controlled substances. They are a speed dirivative.
DH has been on it for 10 years now. He has no problems with his heart or other organs. The side effects he has experienced are dry mouth, some stomach sensitivity, and resistance. The dry mouth is easily remedied since he drinks lots of water. And the stomach is helped with pepto every now and again. His body also becomes more resistant to it over time so the dose goes up every cuple of years by maybe 5 mg (he takes 60 mg). His "positive" side effects are that he isn't all over the board, did well in college, can concentrate at work, and doesn't need much sleep... which will be helpful when we have kids!
From the outside, I hate the occasional day he forgets to take it. He is more like an active 3 year old. His sense of reality is a little odd on those days. But he is wonderful and I love him and I can deal with that because a regular days are, well, normal.