I'd go with the 2 bedroom. Most are dedicated so there is only 1 door to the outside.
Also, you will have a fully equipped kitchen with full size refrigerator and dishwasher (the Inn rooms are like studios). You will have a washer & dryer which can be very, very nice at the beach - especially if you have young children along.
The only advantage to the OV Inn rooms is that you are pretty much guaranteed to have a view of the ocean from the room. But my guess is that the kids will want to be in the pool or the beach or outside enjoying all of the activities and not in the room anyway. And if you do have a "bad weather day", the 2 bedroom will afford much more room for indoor activities (including 3 TVs and a jacuzzi tub).
Have fun.